We are now a participating Health Mart Pharmacy, linked up with the nation's fastest growing independent pharmacy franchise network.  History Little Drug Company, Inc has a long and illustrious history since its beginning in 1920. That was the year Bush-Little Drug Company opened on the northern end of Canal Street. In 1922 Mr. Little bought the business from Mrs. Bush and it became Little Drug Company, relocating to 501 Canal Street. In November of 1965 Little Drug moved across the street to the former Victoria Theater building where it is currently located. Owner, Jerry Sapp, started working at Little Drug in high school and after graduating from college in 1960 came back as a pharmacist. Pharmacy Manager, David Sikes, joined the staff in 1972. Little Drug has the distinction of being the oldest ongoing independent pharmacy in Volusia County. In January 1985, Eli Lilly Pharmacy honored Little Drug for filling its one-millionth prescription. Little Drug has adjusted over the years to the changes of the area and businesses. However, it has maintained the ambiance of the 50's and 60's with an old-fashioned soda fountain and restaurant. We still deliver prescriptions and gift wrap purchases.  We have a full line of American Greeting cards and gift bags. We also have Russell Stover/Whitman candies, Webkins, Trail of Painted Ponies, nautical gifts and much, much more. Make Little Drug Gift Department your shopping headquarters when shopping for loved ones for Valentines Day, St. Patricks Day, Easter and every other holiday and special occasion during the year.